WhatsApp and Signal are two messaging apps dominating the headlines, let's take a look at why - WhatsApp recently updated its privacy policy, stating that the messaging platform will share user data with other Facebook-owned and third-party apps. This has prompted several users to look for alternative platforms, top among them is Signal.
BMC Genomics 18(1):242.Lately, there is a lot of fuss around end-to-end encrypted chat applications. Mallona I, Peinado MA (2017) Truke, a web tool to check for and handle excel misidentified gene symbols.
Neueder A, Gipson TA, Batterton S, Lazell HJ, Farshim PP, Paganetti P, Housman DE, Bates GP (2017) HSF1-dependent and -independent regulation of the mammalian in vivo heat shock response and its impairment in Huntington’s disease mouse models. Ziemann M, Kaspi A, El-Osta A (2019) Digital expression explorer 2: a repository of uniformly processed RNA sequencing data. Lachmann A, Torre D, Keenan AB, Jagodnik KM, Lee HJ, Wang L, Silverstein MC, Ma'ayan A (2018) Massive mining of publicly available RNA-seq data from human and mouse. Ge SX, Son EW, Yao R (2018) iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data.
We also discuss the importance of critical interpretion of results (avoid p-hacking and rationalizing) and validation of significant pathways by using different methods and independent annotation databases.īioconductor DESeq2 Differential gene expression Gene set enrichment analysis Integrated differential expression and pathway analysis Pathway analysis RNA-seq Transcriptomic analysis iDEP. Using a public dataset on the effect of heat shock on mouse with and without functional Hsf1, we demonstrate how users can prepare data files and conduct in-depth analysis. Due to its intuitive user interface and massive annotation database, iDEP is being widely adopted for interactive analysis of RNA-seq data. With iDEP, users can easily conduct exploratory data analysis, identify differentially expressed genes, and perform pathway analysis. We developed a user-friendly web app called iDEP (integrated differential expression and pathway analysis) to help biologists interpret read counts or other types of expression matrices derived from read mapping. RNA sequencing (RNA-seq) has become a routine method for transcriptomic profiling.
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